RNASEH1P1

Across TCGA patient cohorts, RNASEH1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,584 significant associations in total. THYM shows the largest number of these associations.

The most reproducible RNASEH1P1-associated GO terms across cancer lineages are Negative regulation of DNA metabolic process, Maintenance of cell number, and Regulation of cell cycle G2/M phase transition. Each is linked with RNASEH1P1 in more than 17 cancer types. Because this analysis shows association rather than direction, both RNASEH1P1-to-partner and partner-to-RNASEH1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA metabolic process grouped by RNASEH1P1-low versus RNASEH1P1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH1P1→partner) and Y-score (partner→RNASEH1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of DNA metabolic process →	+0.046	+0.631	.002	<.001	2	18
STAD	Maintenance of cell number →	+0.046	+0.418	<.001	<.001	3	16
ESCA	Regulation of cell cycle G2/M phase transition →	+0.068	+0.576	.002	.005	2	17
ESCA	Metaphase chromosome alignment →	+0.087	+0.761	<.001	<.001	3	16
STAD	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.059	+0.495	<.001	<.001	3	15
STAD	Positive regulation of cell cycle phase transition →	+0.045	+0.443	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,584 associations by consensus.

Negative regulation of DNA metabolic process by RNASEH1P1 expression — ESCA

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