Across TCGA patient cohorts, RNASE9 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,136 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNASE9-associated proteins across cancer lineages are COL1A2, COL5A2, and P4HA2. Each is linked with RNASE9 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNASE9-to-partner and partner-to-RNASE9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE9→partner) and Y-score (partner→RNASE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	COL1A2 →	+1.057	+0.130	<.001	<.001	3	5
LUAD	COL5A2 →	+0.586	+0.039	<.001	<.001	3	5
GBM	P4HA2 →	+0.683	+0.097	<.001	<.001	3	5
PDAC	SEC23A →	+0.235	+0.045	.002	.002	3	4
LUAD	BMP1 →	+0.711	+0.049	<.001	<.001	3	4
GBM	CNN2 →	+0.703	+0.084	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,136 associations by consensus.

Exploration

RNASE9 survival (RNA) · tumor vs normal (RNA) · all RNASE9 data types