Across TCGA cell cohorts, RNASE9 RNA expression is significantly associated with the mutation status of many other genes, with 207 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RNASE9-associated genes across cancer lineages are NECTIN1, ACTR1B, and WNK4. Each is linked with RNASE9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNASE9-to-partner and partner-to-RNASE9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE9→partner) and Y-score (partner→RNASE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	NECTIN1 →	+4.614	+0.010	.004	<.001	3	2
PANCREAS	ACTR1B →	+4.614	+0.010	.004	<.001	3	2
URINARY_TRACT	WNK4 →	+5.087	+0.016	.004	<.001	3	2
LUNG_NSCLC_LUSC	CHD5 →	+4.643	+0.040	.008	<.001	3	2
LUNG_SCLC	MCCC1 →	+5.029	+0.029	.006	<.001	3	2
SKIN	WAS →	+5.415	+0.012	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

Exploration

RNASE9 survival (RNA) · tumor vs normal (RNA) · all RNASE9 data types