RNASE7

Across TCGA patient cohorts, RNASE7 protein abundance is significantly associated with the RNA expression of many other genes, with 6,258 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNASE7-associated genes across cancer lineages are MICALL1, MTMR8, and DTWD1. Each is linked with RNASE7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNASE7-to-partner and partner-to-RNASE7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASE7 versus MICALL1 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE7→partner) and Y-score (partner→RNASE7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MICALL1 →	+0.921	+1.113	<.001	.001	3	2
LSCC	MTMR8 →	-0.593	-1.039	.002	<.001	3	2
LSCC	DTWD1 →	-0.526	-1.269	.005	.004	3	2
LSCC	KLC3 →	+1.055	+1.063	.001	.001	3	2
LSCC	SIGLEC8 →	-0.819	-0.988	.006	.003	3	2
LSCC	CNFN →	+2.386	+1.285	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,258 associations by consensus.

RNASE7 vs MICALL1 — LSCC

Explore this scatter interactively →