RNASE7

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNASE7 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,991 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNASE7-associated proteins across cancer lineages are QDPR, BAG3, and CGGBP1. Each is linked with RNASE7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNASE7-to-partner and partner-to-RNASE7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASE7 versus QDPR in LSCC, with a Pearson correlation of -0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE7→partner) and Y-score (partner→RNASE7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCQDPR →-0.309-1.404<.001<.00132
HNSCBAG3 →+0.381+1.695<.001<.00132
HNSCCGGBP1 →-0.434-1.857<.001<.00132
LSCCNCCRP1 →+1.561+1.601<.001<.00132
HNSCPATJ →+0.316+1.206<.001<.00132
HNSCPDCD6IP_S108 →+1.110+3.681.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,991 associations by consensus.

RNASE7 vs QDPR — LSCC

Per-sample scatter of RNASE7 vs QDPR in LSCC (Pearson r = -0.52).

Explore this scatter interactively →

Exploration