RNASE4

Across TCGA patient cohorts, RNASE4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,530 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RNASE4-associated proteins across cancer lineages are GOLPH3L, LMNB2, and MYO1D. Each is linked with RNASE4 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNASE4-to-partner and partner-to-RNASE4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASE4 versus GOLPH3L in COAD, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE4→partner) and Y-score (partner→RNASE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GOLPH3L →	+0.384	+0.466	<.001	.003	3	4
OV	LMNB2 →	+0.265	+0.183	.005	.004	3	4
LUAD	MYO1D →	+0.401	+0.331	<.001	<.001	3	4
BRCA	PTPN1 →	-0.396	-0.351	<.001	.003	3	4
BRCA	PTPN6 →	-0.359	-0.420	<.001	<.001	3	4
LSCC	NDRG2 →	+0.415	+0.323	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,530 associations by consensus.

RNASE4 vs GOLPH3L — COAD

Explore this scatter interactively →