RNASE3

Across TCGA cell cohorts, RNASE3 RNA expression is significantly associated with the RNA expression of many other genes, with 4,973 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNASE3-associated genes across cancer lineages are DEFA1, CTSG, and RNASE2. Each is linked with RNASE3 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNASE3-to-partner and partner-to-RNASE3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASE3 versus DEFA1 in BLOOD_Leukemia, with a Pearson correlation of 0.39.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE3→partner) and Y-score (partner→RNASE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DEFA1 →	+1.995	+2.587	<.001	<.001	3	6
BLOOD_Leukemia	CTSG →	+3.773	+2.328	<.001	<.001	3	4
BLOOD_Leukemia	RNASE2 →	+4.900	+2.599	<.001	<.001	3	4
LUNG_NSCLC_LUAD	CLDN9 →	+1.165	+0.039	<.001	.001	3	3
BLOOD_Leukemia	CD300LF →	+2.777	+2.562	<.001	<.001	3	3
LUNG_NSCLC_LUSC	TAS2R40 →	+0.076	+0.099	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,973 associations by consensus.

RNASE3 vs DEFA1 — BLOOD_Leukemia

Explore this scatter interactively →