RNASE3

Across TCGA cell cohorts, RNASE3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,092 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNASE3-associated GO terms across cancer lineages are Cell surface receptor protein serine/threonine kinase signaling pathway, Vacuolar transport, and Exocytosis. Each is linked with RNASE3 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNASE3-to-partner and partner-to-RNASE3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell surface receptor protein serine/threonine kinase signaling pathway grouped by RNASE3-low versus RNASE3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE3→partner) and Y-score (partner→RNASE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Cell surface receptor protein serine/threonine kinase signaling pathway →	+0.051	+0.040	<.001	.006	3	5
LUNG_NSCLC_LUAD	Vacuolar transport →	+0.034	+0.041	<.001	.002	3	5
LIVER	Exocytosis →	+0.055	+0.092	.001	.002	3	4
SKIN	Regulation of cellular response to osmotic stress →	+0.096	+0.038	.002	.005	3	4
OVARY	Platelet aggregation →	+0.087	+0.033	.004	<.001	3	4
CNS	Actin filament depolymerization →	+0.115	+0.026	.006	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,092 associations by consensus.

Cell surface receptor protein serine/threonine kinase signaling pathway by RNASE3 expression — CNS

Explore this box plot interactively →