RNASE10

Across TCGA cell cohorts, RNASE10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,579 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RNASE10-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Negative regulation of autophagy, and Pre-mRNA catabolic process. Each is linked with RNASE10 in more than 11 cancer types. Because this analysis shows association rather than direction, both RNASE10-to-partner and partner-to-RNASE10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by RNASE10-low versus RNASE10-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE10→partner) and Y-score (partner→RNASE10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Viral translational termination-reinitiation →	+0.081	+0.248	<.001	<.001	3	12
LARGE_INTESTINE	Negative regulation of autophagy →	+0.066	+0.237	<.001	.003	3	11
BONE	Pre-mRNA catabolic process →	+0.217	+0.227	<.001	.005	3	11
BLOOD_Leukemia	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.132	+0.466	<.001	.001	3	11
BONE	Negative regulation of mRNA processing →	+0.101	+0.240	.001	.003	3	11
LARGE_INTESTINE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.072	+0.211	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,579 associations by consensus.

Viral translational termination-reinitiation by RNASE10 expression — SOFT_TISSUE

Explore this box plot interactively →