Across TCGA pan-cancer cohorts, RNA5SP69 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP69’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNA5SP69 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP69 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, LUAD, and THCA are the cancer types where RNA5SP69 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP69 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.255	.001	6	view →
LUAD	All	All	+0.221	.006	2	view →
THCA	Female	All	−0.148	.004	1	view →
KIRP	Male	All	−0.100	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP69 RNA expression & survival · all RNA5SP69 data types