Across TCGA pan-cancer cohorts, RNA5SP68 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP68’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RNA5SP68 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP68 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
STAD and LUSC are the cancer types where RNA5SP68 tumor–normal differential expression is most reproducible.