RNA5SP55

Across TCGA patient cohorts, RNA5SP55 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,940 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNA5SP55-associated GO terms across cancer lineages are RNA destabilization, Regulation of microtubule-based process, and miRNA processing. Each is linked with RNA5SP55 in more than 9 cancer types. Because this analysis shows association rather than direction, both RNA5SP55-to-partner and partner-to-RNA5SP55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA destabilization grouped by RNA5SP55-low versus RNA5SP55-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP55→partner) and Y-score (partner→RNA5SP55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNA destabilization →	+0.042	+0.369	<.001	.002	3	10
ESCA	Regulation of microtubule-based process →	+0.045	+0.551	<.001	<.001	3	10
LUAD	miRNA processing →	+0.054	+0.079	<.001	.001	3	10
ESCA	Positive regulation of mRNA metabolic process →	+0.048	+0.408	<.001	<.001	3	9
ESCA	Cytoplasmic microtubule organization →	+0.050	+0.316	<.001	<.001	3	9
LUAD	Regulatory ncRNA processing →	+0.038	+0.101	<.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,940 associations by consensus.

RNA destabilization by RNA5SP55 expression — ESCA

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