RNA5SP536

Across TCGA pan-cancer cohorts, RNA5SP536 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNA5SP536 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNA5SP536 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP536 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

KICH, KIRC, and UVM are the cancer types where RNA5SP536 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.043	0.971	<.001	99	view →
KIRC	DFS	Tertile	III,IV	0.045	0.757	<.001	90	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
CHOL	OS	Tertile	II,III,IV	0.253	0.796	.018	45	view →
STAD	DFS	Tertile	IV	0.082	0.543	.004	36	view →
HNSC	OS	Tertile	III,IV	0.255	0.678	.013	36	view →
READ	DFS	Tertile	III,IV	0.059	0.761	<.001	36	view →
OV	DFS	Tertile	II,III,IV	0.479	0.367	.031	30	view →
PAAD	DFS	Tertile	All	0.192	0.479	.002	27	view →
ESCA	OS	Tertile	III,IV	0.849	0.354	.019	24	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →
THCA	DFS	Tertile	All	1.000	0.814	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNA5SP536–KICH (DFS)

Open the KICH breakdown →