RNA5SP534

Across TCGA patient cohorts, RNA5SP534 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,266 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNA5SP534-associated GO terms across cancer lineages are Regulation of retrograde protein transport, ER to cytosol, Regulation of protein K63-linked ubiquitination, and Protein exit from endoplasmic reticulum. Each is linked with RNA5SP534 in more than 9 cancer types. Because this analysis shows association rather than direction, both RNA5SP534-to-partner and partner-to-RNA5SP534 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of retrograde protein transport, ER to cytosol grouped by RNA5SP534-low versus RNA5SP534-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP534→partner) and Y-score (partner→RNA5SP534) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of retrograde protein transport, ER to cytosol →	+0.106	+0.163	<.001	<.001	3	10
STAD	Regulation of protein K63-linked ubiquitination →	+0.085	+0.145	<.001	<.001	3	9
STAD	Protein exit from endoplasmic reticulum →	+0.113	+0.166	<.001	<.001	3	9
STAD	Regulation of protein polymerization →	+0.092	+0.154	<.001	<.001	3	9
STAD	Negative regulation of protein exit from endoplasmic reticulum →	+0.106	+0.192	<.001	<.001	3	9
STAD	Regulation of protein serine/threonine kinase activity →	+0.091	+0.177	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,266 associations by consensus.

Regulation of retrograde protein transport, ER to cytosol by RNA5SP534 expression — STAD

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