RNA5SP521

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA5SP521 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,446 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible RNA5SP521-associated GO terms across cancer lineages are Regulation of dendritic spine development, Positive regulation of response to endoplasmic reticulum stress, and Metanephros development. Each is linked with RNA5SP521 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNA5SP521-to-partner and partner-to-RNA5SP521 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dendritic spine development grouped by RNA5SP521-low versus RNA5SP521-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP521→partner) and Y-score (partner→RNA5SP521) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRCRegulation of dendritic spine development →+0.027+0.038<.001.00634
BLCAPositive regulation of response to endoplasmic reticulum stress →+0.036+0.054<.001<.00133
BLCAMetanephros development →+0.019+0.069<.001<.00133
LUSCNegative regulation of RNA splicing →+0.031+0.103<.001<.00133
KIRCRegulation of axonogenesis →+0.041+0.036<.001<.00133
HNSCPositive regulation of TOR signaling →+0.024+0.055.007.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,446 associations by consensus.

Regulation of dendritic spine development by RNA5SP521 expression — KIRC

Box plot of Regulation of dendritic spine development in RNA5SP521-low vs RNA5SP521-high samples in KIRC.

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Exploration