Across TCGA pan-cancer cohorts, RNA5SP511 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP511’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNA5SP511 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP511 is over-expressed in tumor.
KIRC and ESCA are the cancer types where RNA5SP511 tumor–normal differential expression is most reproducible.