Across TCGA pan-cancer cohorts, RNA5SP492 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP492’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNA5SP492 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP492 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC, BRCA, and COAD are the cancer types where RNA5SP492 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP492 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.233	.001	4	view →
BRCA	Female	All	+0.171	.007	4	view →
COAD	All	All	+0.086	.028	3	view →
HNSC	All	II,III,IV	+0.113	.023	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP492 RNA expression & survival · all RNA5SP492 data types