RNA5SP49

Across TCGA pan-cancer cohorts, RNA5SP49 RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNA5SP49 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RNA5SP49 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNA5SP49 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

CESC, ESCA, and STAD are the cancer types where RNA5SP49 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	All	0.068	0.875	<.001	108	view →
ESCA	OS	Tertile	III,IV	1.000	0.372	.033	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
BLCA	DFS	Tertile	III,IV	0.159	0.572	.036	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNA5SP49–CESC (OS)

Open the CESC breakdown →