Across TCGA pan-cancer cohorts, RNA5SP48 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP48’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RNA5SP48 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP48 is over-expressed in tumor.
BRCA, STAD, and LUSC are the cancer types where RNA5SP48 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP48 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.