RNA5SP476

Across TCGA pan-cancer cohorts, RNA5SP476 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP476’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNA5SP476 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP476 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, KICH, and THCA are the cancer types where RNA5SP476 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP476 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.195	<.001	8	view →
KICH	All	All	−0.296	.003	4	view →
THCA	All	All	−0.146	.008	2	view →
KIRP	All	II,III,IV	+0.245	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNA5SP476–KIRC

Open the KIRC breakdown →