Across TCGA pan-cancer cohorts, RNA5SP463 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP463’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNA5SP463 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP463 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, UCEC, and COAD are the cancer types where RNA5SP463 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP463 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.312	.012	8	view →
UCEC	All	All	+0.356	.020	2	view →
COAD	All	II,III,IV	+0.138	.049	1	view →
THCA	All	All	−0.081	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP463 RNA expression & survival · all RNA5SP463 data types