RNA5SP461

Across TCGA patient cohorts, RNA5SP461 RNA expression is significantly associated with the mutation status of many other genes, with 1,181 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RNA5SP461-associated genes across cancer lineages are CACNA2D2, CFAP61, and DENND2A. Each is linked with RNA5SP461 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNA5SP461-to-partner and partner-to-RNA5SP461 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CACNA2D2 grouped by RNA5SP461-low versus RNA5SP461-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP461→partner) and Y-score (partner→RNA5SP461) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CACNA2D2 →	+3.772	+0.044	.005	<.001	3	4
SKCM	CFAP61 →	+3.647	+0.041	.006	<.001	3	4
SKCM	DENND2A →	+4.062	+0.053	.003	<.001	3	3
SKCM	HAS2 →	+5.816	+0.156	<.001	<.001	3	3
SKCM	UGT2B7 →	+4.009	+0.052	.004	<.001	3	3
SKCM	CNBD1 →	+4.357	+0.065	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,181 associations by consensus.

CACNA2D2 by RNA5SP461 expression — SKCM

Explore this box plot interactively →