RNA5SP460

Across TCGA pan-cancer cohorts, RNA5SP460 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNA5SP460 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RNA5SP460 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNA5SP460 expression acts as an unfavorable survival marker, although some lineages such as LAML and GBM show a favorable association.

LUSC, CHOL, and CESC are the cancer types where RNA5SP460 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	II,III,IV	0.205	0.627	<.001	60	view →
CHOL	DFS	Tertile	All	0.045	0.486	.009	45	view →
CESC	DFS	Tertile	All	0.173	0.740	.003	36	view →
LIHC	OS	Tertile	II,III,IV	0.196	0.719	.002	36	view →
KIRP	OS	Tertile	All	0.141	0.708	<.001	36	view →
LAML	DFS	Quartile	All	0.852	0.515	.014	28	view →
GBM	DFS	Tertile	All	1.000	0.183	.001	27	view →
STAD	DFS	Tertile	All	0.167	0.413	.005	27	view →
PCPG	DFS	Tertile	All	0.118	0.828	<.001	18	view →
MESO	DFS	Tertile	All	0.277	0.215	.006	12	view →
LUAD	DFS	Tertile	II,III,IV	1.000	0.401	.025	12	view →
THCA	OS	Tertile	IV	0.252	1.000	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

RNA5SP460–LUSC (OS)

Open the LUSC breakdown →