RNA5SP458

Across TCGA pan-cancer cohorts, RNA5SP458 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNA5SP458 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher RNA5SP458 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNA5SP458 expression acts as an unfavorable survival marker, although some lineages such as OV and ESCA show a favorable association.

STAD, COAD, and ACC are the cancer types where RNA5SP458 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	III,IV	0.306	0.638	.004	54	view →
COAD	OS	Tertile	II,III,IV	0.164	0.789	<.001	45	view →
ACC	DFS	Tertile	II,III,IV	0.063	0.640	<.001	36	view →
LIHC	OS	Tertile	All	0.047	0.783	<.001	27	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
UCEC	DFS	Tertile	All	0.685	0.844	.014	18	view →
OV	OS	Tertile	All	0.985	0.834	.047	12	view →
LUAD	DFS	Tertile	All	0.325	0.682	.012	9	view →
ESCA	OS	Tertile	III,IV	1.000	0.376	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RNA5SP458–STAD (OS)

Open the STAD breakdown →