RNA5SP445

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP445 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNA5SP445 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNA5SP445 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP445 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

KICH, UCS, and KIRC are the cancer types where RNA5SP445 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHDFSTertileII,III,IV0.0420.883<.001108view →
UCSOSTertileAll0.0010.690<.001108view →
KIRCDFSTertileIII,IV0.2130.519<.001108view →
UCECDFSTertileAll0.7770.899.00472view →
BLCAOSTertileIV0.1790.599.00827view →
READDFSTertileIV0.0270.636<.00127view →
ACCDFSTertileIII,IV0.0480.457.01518view →
OVDFSTertileIII,IV0.3250.536.01812view →
COADOSTertileIV0.1400.657.0359view →
GBMOSTertileAll0.3110.172.0306view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNA5SP445–KICH (DFS)

Kaplan–Meier survival curve for RNA5SP445 RNA-high vs -low samples in KICH.

Open the KICH breakdown →

Exploration