Across TCGA pan-cancer cohorts, RNA5SP442 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP442’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNA5SP442 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP442 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

LUSC, BRCA, and THCA are the cancer types where RNA5SP442 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP442 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.459	.001	4	view →
BRCA	Female	All	−0.190	<.001	4	view →
THCA	All	All	−0.182	<.001	3	view →
HNSC	Male	II,III,IV	−0.064	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP442 RNA expression & survival · all RNA5SP442 data types