RNA5SP437

Across TCGA pan-cancer cohorts, RNA5SP437 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RNA5SP437’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNA5SP437 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP437 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

STAD, LUSC, and BLCA are the cancer types where RNA5SP437 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP437 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	II,III,IV	+0.394	.013	4	view →
LUSC	All	II,III,IV	+0.266	.004	3	view →
BLCA	All	All	+0.265	.039	2	view →
UCEC	All	All	+0.203	.044	2	view →
COAD	All	III,IV	−0.148	.032	2	view →
HNSC	All	II,III,IV	+0.085	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RNA5SP437–STAD

Open the STAD breakdown →