RNA5SP436

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP436 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RNA5SP436’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNA5SP436 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP436 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA are the cancer types where RNA5SP436 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP436 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAAllAll−0.096.0013view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

RNA5SP436–THCA

Tumor-vs-normal expression box plot for RNA5SP436 RNA in THCA.

Open the THCA breakdown →

Exploration