RNA5SP434

Across TCGA pan-cancer cohorts, RNA5SP434 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP434’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RNA5SP434 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP434 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD and KICH are the cancer types where RNA5SP434 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP434 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	−0.551	.001	4	view →
KICH	Male	IV	−0.350	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RNA5SP434–COAD

Open the COAD breakdown →