RNA5SP428

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP428 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RNA5SP428 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNA5SP428 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP428 expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

UCS, HNSC, and CESC are the cancer types where RNA5SP428 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSDFSTertileAll0.0680.524<.001144view →
HNSCOSTertileII,III,IV0.0590.712<.00175view →
CESCOSTertileAll0.1330.595.00154view →
THCADFSTertileII,III,IV0.1450.794.00136view →
MESODFSTertileIII,IV0.1430.419.01536view →
GBMOSTertileAll0.2170.424.01818view →
PRADOSTertileAll0.8260.990<.00118view →
SARCDFSTertileAll0.1610.517.04015view →
LIHCDFSTertileAll0.1190.555.0089view →
COADDFSTertileAll0.8910.769.0376view →
ESCAOSTertileAll0.5630.709.0473view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration