RNA5SP423

Across TCGA patient cohorts, RNA5SP423 RNA expression is significantly associated with the mutation status of many other genes, with 3,931 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNA5SP423-associated genes across cancer lineages are VPS13B, DROSHA, and CAPN13. Each is linked with RNA5SP423 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNA5SP423-to-partner and partner-to-RNA5SP423 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VPS13B grouped by RNA5SP423-low versus RNA5SP423-high in UCS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP423→partner) and Y-score (partner→RNA5SP423) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	VPS13B →	+4.700	+0.985	.004	<.001	3	4
LUSC	DROSHA →	+3.511	+0.380	.002	<.001	3	4
ESCA	CAPN13 →	+5.285	+0.240	.002	<.001	3	3
BRCA	ARMC8 →	+7.731	+0.260	.009	<.001	3	3
LUSC	USP11 →	+4.412	+0.369	.006	.002	3	3
CESC	RUNX2 →	+5.252	+0.358	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,931 associations by consensus.

VPS13B by RNA5SP423 expression — UCS

Explore this box plot interactively →