RNA5SP421

Across TCGA patient cohorts, RNA5SP421 RNA expression is significantly associated with the mutation status of many other genes, with 4,162 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNA5SP421-associated genes across cancer lineages are CSMD3, LYST, and GABRE. Each is linked with RNA5SP421 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNA5SP421-to-partner and partner-to-RNA5SP421 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSMD3 grouped by RNA5SP421-low versus RNA5SP421-high in ESCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP421→partner) and Y-score (partner→RNA5SP421) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	CSMD3 →	+2.709	+0.063	.004	<.001	3	4
UCS	LYST →	+5.700	+1.496	.002	<.001	3	3
LUSC	GABRE →	+6.023	+1.032	<.001	<.001	3	3
LUSC	SEMA5A →	+3.438	+0.345	<.001	<.001	3	3
LUSC	PREX1 →	+3.268	+0.423	<.001	<.001	3	3
LUSC	ST3GAL3 →	+6.438	+1.410	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,162 associations by consensus.

CSMD3 by RNA5SP421 expression — ESCA

Explore this box plot interactively →