RNA5SP421

Across TCGA patient cohorts, RNA5SP421 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,910 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNA5SP421-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Positive regulation of intracellular protein transport, and Positive regulation of protein kinase activity. Each is linked with RNA5SP421 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNA5SP421-to-partner and partner-to-RNA5SP421 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by RNA5SP421-low versus RNA5SP421-high in BLCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP421→partner) and Y-score (partner→RNA5SP421) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Establishment of protein localization to membrane →	+0.026	+0.014	.006	.005	3	5
KIRC	Positive regulation of intracellular protein transport →	+0.036	+0.035	<.001	<.001	3	4
KIRC	Positive regulation of protein kinase activity →	+0.028	+0.032	<.001	<.001	3	4
KIRC	Positive regulation of viral process →	+0.037	+0.033	<.001	.004	3	4
KIRC	Negative regulation of DNA metabolic process →	+0.030	+0.053	<.001	<.001	3	4
STAD	Regulation of mRNA catabolic process →	+0.092	+0.050	<.001	.004	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,910 associations by consensus.

Establishment of protein localization to membrane by RNA5SP421 expression — BLCA

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