RNA5SP418

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA5SP418 RNA expression is significantly associated with the mutation status of many other genes, with 4,071 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNA5SP418-associated genes across cancer lineages are HCN1, CSMD2, and INVS. Each is linked with RNA5SP418 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNA5SP418-to-partner and partner-to-RNA5SP418 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HCN1 grouped by RNA5SP418-low versus RNA5SP418-high in UCEC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP418→partner) and Y-score (partner→RNA5SP418) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHCN1 →+1.155+0.351.006<.00134
BRCACSMD2 →+3.921+0.073.007.00333
STADINVS →+5.091+0.141.002<.00133
STADZNF665 →+4.506+0.171.004<.00133
LUSCFAF2 →+5.978+0.548.002.00733
LUSCMYO18B →+2.052+0.220.006<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,071 associations by consensus.

HCN1 by RNA5SP418 expression — UCEC

Box plot of HCN1 in RNA5SP418-low vs RNA5SP418-high samples in UCEC.

Explore this box plot interactively →

Exploration