RNA5SP411

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA5SP411 RNA expression is significantly associated with the mutation status of many other genes, with 5,948 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNA5SP411-associated genes across cancer lineages are PREX1, HIVEP2, and MYEF2. Each is linked with RNA5SP411 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNA5SP411-to-partner and partner-to-RNA5SP411 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PREX1 grouped by RNA5SP411-low versus RNA5SP411-high in LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP411→partner) and Y-score (partner→RNA5SP411) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCPREX1 →+3.070+0.247.005<.00135
KIRCHIVEP2 →+6.203+0.188<.001.00234
UCECMYEF2 →+1.570+0.902.001<.00134
UCECRBBP6 →+1.352+0.614.002<.00134
UCECDOCK5 →+1.306+0.661.003<.00134
BRCAABCC5 →+6.145+0.299<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,948 associations by consensus.

PREX1 by RNA5SP411 expression — LUSC

Box plot of PREX1 in RNA5SP411-low vs RNA5SP411-high samples in LUSC.

Explore this box plot interactively →

Exploration