RNA5SP40

Across TCGA pan-cancer cohorts, RNA5SP40 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNA5SP40 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNA5SP40 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNA5SP40 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

KIRP, STAD, and TGCT are the cancer types where RNA5SP40 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.728	0.883	.001	42	view →
STAD	DFS	Tertile	All	0.413	0.732	.001	39	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	36	view →
LUAD	OS	Tertile	III,IV	0.793	0.313	.011	30	view →
UVM	OS	Tertile	All	0.368	0.757	.005	22	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	21	view →
SKCM	DFS	Quartile	IV	0.615	0.112	.017	7	view →
KIRC	DFS	Median	IV	0.470	0.242	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RNA5SP40–KIRP (DFS)

Open the KIRP breakdown →