Across TCGA pan-cancer cohorts, RNA5SP390 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP390’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNA5SP390 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP390 is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

LUSC, BRCA, and LUAD are the cancer types where RNA5SP390 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP390 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.285	.016	2	view →
BRCA	All	III,IV	−0.237	.032	2	view →
LUAD	Female	III,IV	−0.393	.031	1	view →
KIRC	Female	All	+0.147	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP390 RNA expression & survival · all RNA5SP390 data types