Across TCGA pan-cancer cohorts, RNA5SP39 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP39’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNA5SP39 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP39 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

KICH, LUSC, and CHOL are the cancer types where RNA5SP39 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP39 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.350	.001	5	view →
LUSC	All	All	−0.315	.010	3	view →
CHOL	Male	All	+0.960	.004	2	view →
KIRC	All	All	+0.277	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP39 RNA expression & survival · all RNA5SP39 data types