RNA5SP386

Across TCGA patient cohorts, RNA5SP386 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,043 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNA5SP386-associated GO terms across cancer lineages are Positive regulation of protein modification by small protein conjugation or removal, Cytosolic transport, and Regulation of proteasomal ubiquitin-dependent protein catabolic process. Each is linked with RNA5SP386 in more than 14 cancer types. Because this analysis shows association rather than direction, both RNA5SP386-to-partner and partner-to-RNA5SP386 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein modification by small protein conjugation or removal grouped by RNA5SP386-low versus RNA5SP386-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP386→partner) and Y-score (partner→RNA5SP386) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of protein modification by small protein conjugation or removal →	+0.065	+0.504	<.001	<.001	3	15
ESCA	Cytosolic transport →	+0.054	+0.385	<.001	<.001	3	15
ESCA	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.059	+0.400	.002	<.001	3	15
ESCA	Regulation of proteolysis involved in protein catabolic process →	+0.061	+0.390	<.001	<.001	3	15
STAD	Lipoprotein biosynthetic process →	+0.047	+0.284	<.001	<.001	3	15
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.064	+0.432	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,043 associations by consensus.

Positive regulation of protein modification by small protein conjugation or removal by RNA5SP386 expression — ESCA

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