Across TCGA pan-cancer cohorts, RNA5SP382 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNA5SP382’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNA5SP382 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP382 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.
KIRC, BRCA, and LUSC are the cancer types where RNA5SP382 tumor–normal differential expression is most reproducible.