Across TCGA pan-cancer cohorts, RNA5SP38 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP38’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RNA5SP38 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP38 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

STAD, LUSC, and HNSC are the cancer types where RNA5SP38 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP38 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.550	.001	6	view →
LUSC	All	All	+0.130	.015	4	view →
HNSC	Male	II,III,IV	+0.120	.030	4	view →
COAD	All	II,III,IV	−0.220	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNA5SP38 RNA expression & survival · all RNA5SP38 data types