Across TCGA pan-cancer cohorts, RNA5SP366 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RNA5SP366’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RNA5SP366 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP366 is over-expressed in tumor.
BRCA and COAD are the cancer types where RNA5SP366 tumor–normal differential expression is most reproducible.