RNA5SP365

Across TCGA patient cohorts, RNA5SP365 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,688 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNA5SP365-associated GO terms across cancer lineages are Positive regulation of double-strand break repair via homologous recombination, Nucleobase-containing compound transport, and Regulation of telomere maintenance. Each is linked with RNA5SP365 in more than 10 cancer types. Because this analysis shows association rather than direction, both RNA5SP365-to-partner and partner-to-RNA5SP365 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair via homologous recombination grouped by RNA5SP365-low versus RNA5SP365-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP365→partner) and Y-score (partner→RNA5SP365) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of double-strand break repair via homologous recombination →	+0.058	+0.279	<.001	.001	3	11
ESCA	Nucleobase-containing compound transport →	+0.072	+0.319	<.001	<.001	3	11
ESCA	Regulation of telomere maintenance →	+0.081	+0.264	<.001	<.001	3	11
ESCA	Regulation of cilium assembly →	+0.060	+0.318	<.001	<.001	3	10
ESCA	Positive regulation of DNA biosynthetic process →	+0.075	+0.258	<.001	.001	3	10
ESCA	Positive regulation of DNA recombination →	+0.063	+0.160	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,688 associations by consensus.

Positive regulation of double-strand break repair via homologous recombination by RNA5SP365 expression — ESCA

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