RNA5SP351

Across TCGA pan-cancer cohorts, RNA5SP351 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNA5SP351’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RNA5SP351 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP351 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

KIRP, LUSC, and THCA are the cancer types where RNA5SP351 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP351 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	+0.213	.005	5	view →
LUSC	All	II,III,IV	−0.164	.003	2	view →
THCA	All	All	−0.120	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

RNA5SP351–KIRP

Open the KIRP breakdown →