Across TCGA pan-cancer cohorts, RNA5SP345 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RNA5SP345’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where RNA5SP345 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP345 is over-expressed in tumor.

PAAD, KIRC, and LUSC are the cancer types where RNA5SP345 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP345 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	All	All	+0.647	.023	2	view →
KIRC	All	II,III,IV	+0.218	.018	2	view →
LUSC	Female	III,IV	+0.720	.003	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNA5SP345 RNA expression & survival · all RNA5SP345 data types