RNA5SP342

Across TCGA pan-cancer cohorts, RNA5SP342 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNA5SP342’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RNA5SP342 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP342 is over-expressed in tumor, although a few such as PRAD show the opposite, repressed pattern.

HNSC, LUSC, and PRAD are the cancer types where RNA5SP342 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP342 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.735	.006	7	view →
LUSC	All	All	+0.384	.001	4	view →
PRAD	All	All	−0.188	.046	2	view →
KIRC	Male	All	+0.109	.042	2	view →
STAD	Male	All	+0.290	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RNA5SP342–HNSC

Open the HNSC breakdown →