RNA5SP340

Across TCGA patient cohorts, RNA5SP340 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,391 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible RNA5SP340-associated GO terms across cancer lineages are Regulation of DNA recombination, RNA 3'-end processing, and Regulation of DNA repair. Each is linked with RNA5SP340 in more than 12 cancer types. Because this analysis shows association rather than direction, both RNA5SP340-to-partner and partner-to-RNA5SP340 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA recombination grouped by RNA5SP340-low versus RNA5SP340-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNA5SP340→partner) and Y-score (partner→RNA5SP340) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA recombination →	+0.042	+0.193	.001	<.001	3	13
ESCA	RNA 3'-end processing →	+0.046	+0.249	<.001	<.001	3	13
ESCA	Regulation of DNA repair →	+0.044	+0.234	.001	<.001	3	13
ESCA	Response to ionizing radiation →	+0.045	+0.200	.001	<.001	3	12
STAD	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.051	+0.133	<.001	<.001	3	12
ESCA	Regulation of telomere maintenance →	+0.045	+0.242	.002	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,391 associations by consensus.

Regulation of DNA recombination by RNA5SP340 expression — ESCA

Explore this box plot interactively →