RNA5SP33

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP33 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNA5SP33 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNA5SP33 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNA5SP33 expression acts as an unfavorable survival marker, although some lineages such as STAD and BLCA show a favorable association.

MESO, CHOL, and STAD are the cancer types where RNA5SP33 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileAll0.0840.560<.00163view →
CHOLOSTertileIII,IV0.1360.859.00345view →
STADDFSMedianIV0.7970.118<.00137view →
DLBCOSTertileII,III,IV0.0960.865<.00136view →
UCSDFSTertileIV0.1320.718.00236view →
THCADFSTertileIII,IV0.6770.847.00927view →
SKCMDFSTertileIV0.0400.620.00318view →
ACCOSTertileIV0.3270.633.04518view →
PRADOSTertileAll0.6490.914<.00118view →
READDFSTertileIII,IV0.2550.757.00818view →
LIHCOSTertileAll0.3730.720<.00118view →
BLCAOSTertileIV0.7450.556.03112view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

RNA5SP33–MESO (OS)

Kaplan–Meier survival curve for RNA5SP33 RNA-high vs -low samples in MESO.

Open the MESO breakdown →

Exploration