Across TCGA pan-cancer cohorts, RNA5SP320 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP320’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where RNA5SP320 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP320 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.
UCEC, KIRP, and KIRC are the cancer types where RNA5SP320 tumor–normal differential expression is most reproducible.