RNA5SP311

Across TCGA pan-cancer cohorts, RNA5SP311 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RNA5SP311 data layer compared with 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNA5SP311 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNA5SP311 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LAML show a favorable association.

HNSC, ACC, and STAD are the cancer types where RNA5SP311 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.707	0.546	<.001	74	view →
ACC	DFS	Median	All	0.319	0.777	<.001	53	view →
STAD	OS	Median	III,IV	0.505	0.750	.004	50	view →
UCEC	DFS	Tertile	All	0.399	0.669	.002	48	view →
DLBC	DFS	Tertile	III,IV	0.074	0.984	.003	42	view →
LAML	DFS	Tertile	All	0.521	0.245	.009	30	view →
BRCA	OS	Median	All	0.946	0.902	.002	26	view →
KIRC	DFS	Median	II,III,IV	0.438	0.630	.007	23	view →
SKCM	DFS	Tertile	IV	0.217	0.593	.024	19	view →
PRAD	OS	Tertile	All	0.849	0.954	.006	18	view →
LGG	DFS	Median	All	0.541	0.316	.001	17	view →
OV	OS	Quartile	All	0.289	0.407	.012	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RNA5SP311–HNSC (DFS)

Open the HNSC breakdown →